On December 29th, the team of Professor Wu Depei and Xu Yang from the First Affiliated Hospital of Soochow University and Professor Zheng Hui from Soochow University cooperated in publishing the latest research paper with the title of “The OTUD1-Notch2-ICD axis orchestrates allogeneic T cell-mediated graft-versus-host disease” in Blood online. In the paper, the mechanism of OTUD1-drivenNICD signaling promoting T cell-mediated allogeneic responses and the alleviation of aGVHD was reported.
Link: https://doi.org/10.1182/blood.2022017201